Brantôme (Brantòsme in Occitan) is a commune in the Dordogne department in southwestern France. It is the seat of the canton of Brantôme. Via Lemovicensis (fr), an old pilgrimage route to Santiago de Compostela, runs through Brantôme. The commune, which retains its picturesque atmosphere, is situated along the river Dronne.
The Côle forms part of the commune's north-eastern border, then flows into the Dronne, which flows southwestward through the middle of the commune.